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对这家制药巨头来说,新冠疫情是把双刃剑

受新冠疫情影响,由于全球各地纷纷祭出“封城”政策,罗氏的其他药品的销售大幅下降。

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对市值仅次于雀巢(Nestlé)的欧洲第二大公司罗氏(Roche)而言,新冠疫情可谓福祸相依。

检测试剂盒及其知名鸡尾酒疗法(曾经提供给美国前总统唐纳德•特朗普)亮眼的销售成绩为这家瑞士医疗巨头上半年的业绩提供了有力支撑,大大弥补了该公司制药部门因为廉价仿制药竞争而出现收缩留下的营收缺口。

但受新冠疫情影响,由于全球各地纷纷祭出“封城”政策,愿意或能够接受治疗的患者人数显著减少,罗氏的其他药品的销售大幅下降。此外,随着新冠疫苗接种率持续上升,未来新冠检测的需求走向仍不明朗。

该公司的首席执行官施万(Severin Schwan)在一份声明中警告称:“不出所料,新冠检测需求在第二季度已达顶峰。”

今年4月,罗氏以19亿美元的价格收购了美国分子诊断上市公司GenMark,旗下诊断部门的营收随之大幅增长,营收增长了一倍有余。事实上,罗氏今年前六个月的营收增长均可归功于其各项新冠检测产品,相关产品的营收增长接近四倍,达到25亿瑞士法郎(约27亿美元)。

另外5.95亿瑞士法郎的增量营收来自Ronapreve,这是一种由罗氏与再生元(Regeneron)共同开发的全新抗体疗法,去年,美国前总统特朗普在感染新冠肺炎时便使用了这种疗法。

受新冠疫情相关限制措施及有关当局不时祭出封城政策的影响,许多病人减少了找医生或去医院看病的次数,老年人尤其如此。许多医院和医疗保健机构被迫推迟或取消了一些非必要的手术。

这种情况也打压了罗氏多发性硬化症治疗药物奥瑞珠单抗(Ocrevus)的市场需求。新冠疫情期间,该产品一举超过阿瓦斯汀(Avastin),拿下了罗氏最畅销产品的桂冠,成为产品线上的一大亮点。

该款药物的销售营收飙升23%至24亿瑞士法郎,但如果没有新冠疫情,其销售额还将更高。由于奥瑞珠单抗需要通过静脉输液输入体内,所以相关患者必须去医院就诊,但在某些情况下,就诊预约会被推迟或取消。

阿尔茨海默症治疗药物的研发进展

施万承认,在失去阿瓦斯汀这种“摇钱树”式畅销产品的专利保护之后,竞争对手的廉价药物正在侵蚀该公司体量更大、利润更丰厚的制药业务。

受去年下半年欧洲新款廉价竞品进入市场的影响,该款用于治疗多种晚期癌症的药物的销售额下降至16.5亿瑞士法郎,降幅达到了40%。

尽管施万声称罗氏的研究人员在新药研发上取得了“重大进展”,但在明年临床试验预期结果出来之前,关于其阿尔茨海默症治疗新药Gantenerumab的介绍却寥寥无几。

自美国食品与药品管理局(FDA)在今年6月批准渤建(Biogen)的Aduhelm用于治疗这种老年疾病以及礼来(Eli Lilly)宣布在donanemab的药物研发方面取得进展后,分析师预计,罗氏在这方面的药物研发将成为推动该公司股价上升的关键催化剂。

瑞银(UBS)在一份研究报告中写道:“表面上看,罗氏上半年的业绩可圈可点,但这两个部门的很大一块业绩来自于新冠疫情的影响。”瑞银还补充称,未来投资者关注的焦点将是Gantenerumab(一种阿尔茨海默症治疗药物)。

罗氏表示,按固定汇率计算,预计公司今年销售额、收益仍将实现中低水平个位数增长,由此,分红也会有所增加。(财富中文网)

译者:梁宇

审校:夏林

对市值仅次于雀巢(Nestlé)的欧洲第二大公司罗氏(Roche)而言,新冠疫情可谓福祸相依。

检测试剂盒及其知名鸡尾酒疗法(曾经提供给美国前总统唐纳德•特朗普)亮眼的销售成绩为这家瑞士医疗巨头上半年的业绩提供了有力支撑,大大弥补了该公司制药部门因为廉价仿制药竞争而出现收缩留下的营收缺口。

但受新冠疫情影响,由于全球各地纷纷祭出“封城”政策,愿意或能够接受治疗的患者人数显著减少,罗氏的其他药品的销售大幅下降。此外,随着新冠疫苗接种率持续上升,未来新冠检测的需求走向仍不明朗。

该公司的首席执行官施万(Severin Schwan)在一份声明中警告称:“不出所料,新冠检测需求在第二季度已达顶峰。”

今年4月,罗氏以19亿美元的价格收购了美国分子诊断上市公司GenMark,旗下诊断部门的营收随之大幅增长,营收增长了一倍有余。事实上,罗氏今年前六个月的营收增长均可归功于其各项新冠检测产品,相关产品的营收增长接近四倍,达到25亿瑞士法郎(约27亿美元)。

另外5.95亿瑞士法郎的增量营收来自Ronapreve,这是一种由罗氏与再生元(Regeneron)共同开发的全新抗体疗法,去年,美国前总统特朗普在感染新冠肺炎时便使用了这种疗法。

受新冠疫情相关限制措施及有关当局不时祭出封城政策的影响,许多病人减少了找医生或去医院看病的次数,老年人尤其如此。许多医院和医疗保健机构被迫推迟或取消了一些非必要的手术。

这种情况也打压了罗氏多发性硬化症治疗药物奥瑞珠单抗(Ocrevus)的市场需求。新冠疫情期间,该产品一举超过阿瓦斯汀(Avastin),拿下了罗氏最畅销产品的桂冠,成为产品线上的一大亮点。

该款药物的销售营收飙升23%至24亿瑞士法郎,但如果没有新冠疫情,其销售额还将更高。由于奥瑞珠单抗需要通过静脉输液输入体内,所以相关患者必须去医院就诊,但在某些情况下,就诊预约会被推迟或取消。

阿尔茨海默症治疗药物的研发进展

施万承认,在失去阿瓦斯汀这种“摇钱树”式畅销产品的专利保护之后,竞争对手的廉价药物正在侵蚀该公司体量更大、利润更丰厚的制药业务。

受去年下半年欧洲新款廉价竞品进入市场的影响,该款用于治疗多种晚期癌症的药物的销售额下降至16.5亿瑞士法郎,降幅达到了40%。

尽管施万声称罗氏的研究人员在新药研发上取得了“重大进展”,但在明年临床试验预期结果出来之前,关于其阿尔茨海默症治疗新药Gantenerumab的介绍却寥寥无几。

自美国食品与药品管理局(FDA)在今年6月批准渤建(Biogen)的Aduhelm用于治疗这种老年疾病以及礼来(Eli Lilly)宣布在donanemab的药物研发方面取得进展后,分析师预计,罗氏在这方面的药物研发将成为推动该公司股价上升的关键催化剂。

瑞银(UBS)在一份研究报告中写道:“表面上看,罗氏上半年的业绩可圈可点,但这两个部门的很大一块业绩来自于新冠疫情的影响。”瑞银还补充称,未来投资者关注的焦点将是Gantenerumab(一种阿尔茨海默症治疗药物)。

罗氏表示,按固定汇率计算,预计公司今年销售额、收益仍将实现中低水平个位数增长,由此,分红也会有所增加。(财富中文网)

译者:梁宇

审校:夏林

The Coronavirus pandemic is proving to be both a blessing and a curse for Roche, Europe’s second most valuable company after Nestlé.

Selling testing kits and a COVID-19 drug cocktail famously given to then-President Donald Trump propped up first-half results at the Swiss healthcare giant, and more than made up for a contraction in the company’s broader pharmaceuticals division beset by cheaper copycat generics.

Yet the virus also cost Roche in the form of lost pharmaceutical sales for the company's other treatments as fewer patients were willing or able to go for treatment due to global lockdowns. Moreover, demand for its COVID diagnostics going forward remains uncertain as vaccinations rates continue to rise.

“As expected, demand for COVID-19 tests peaked in the second quarter,” Chief Executive Severin Schwan warned in a statement.

Revenue surged and earnings more than doubled in its diagnostics division, which Roche bolstered in April through the $1.9 billion acquisition of U.S. provider GenMark. In fact Roche’s entire topline growth during the first six months of the year can be attributed to revenue from its various COVID-19 tests nearly quadrupling to 2.5 billion Swiss francs ($2.7 billion).

Another 595 million francs in incremental turnover came from sales of Ronapreve, a new therapy developed together with Regeneron that was used to treat Trump when he contracted the virus while in office last year.

Pandemic-related restrictions and rolling lockdowns discouraged some patients from visiting their physicians and hospitals, especially affecting the elderly. Many hospitals and healthcare practices were forced to delay or cancel non-critical procedures.

This hurt demand for Roche's multiple sclerosis treatment Ocrevus, for example, a bright spot in the company's drug portfolio that overtook Avastin as the group’s top seller during the period.

Revenue for this drug soared 23% to 2.4 billion francs, but it would have been even higher had it not been for COVID. Administered via intravenous infusion, Ocrevus requires hospital visits which were in some cases cancelled or delayed.

An eye on Alzheimer's treatments

Schwan acknowledged cheaper rival medications were cutting into his company’s larger and more lucrative pharma business after the loss of patent protection on cash cows like its previous best-seller Avastin.

The drug, which treats a variety of advanced cancers, saw a 40% drop in sales to 1.65 billion francs, driven by new, cheaper competition in Europe that entered the market in the latter half of last year.

While Schwan claimed Roche researchers were making “significant progress” on its product pipeline for new drugs, little was said about its new Alzheimer’s treatment Gantenerumab in advance of next year’s expected results of a clinical trial.

Ever since the FDA approved in June Biogen’s Aduhelm treatment for the debilitating disease and Eli Lilly's advances with its treatment donanemab, analysts expect news on Roche’s own treatment will serve as a key catalyst for the shares.

“Cosmetically a good H1, but a large proportion of the beat in both divisions is COVID driven,” wrote UBS in a research note, adding that investor focus going forward will be on gantenerumab.

Roche said it continues to expect sales and earnings to grow this year by a low to mid-single digit percentage rate at constant exchange rates, leading to an increase in its dividend.

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