一种被用于治疗哮喘病发作的常见药物沙丁胺醇供应短缺,加剧了患者以及提供药物的药店和医疗设施的焦虑。
据美国食品与药品管理局(U.S. Food and Drug Administration)表示,硫酸沙丁胺醇吸入溶液自2022年秋天以来面临供应短缺。跟踪药物短缺情况的美国卫生系统药师协会(American Society of Health-System Pharmacists)称,该药物的主要生产商Akorn在今年2月关闭,严重影响了供应链。
沙丁胺醇是一种支气管扩张剂,可以通过放松气道的平滑肌来缓解哮喘病发作。美国呼吸治疗学会(American Association for Respiratory Care)的主席卡尔·欣克森对《财富》杂志表示,该药物还被用于治疗呼吸道合胞病毒(RSV)等呼吸道疾病,以及慢性阻塞性肺病(简称COPD,又被称为肺气肿)等慢性呼吸道疾病。
哪些人会受到影响?如果医生曾经为你开具沙丁胺醇处方,并且你尚未受到影响,未来你是否会受影响?关于这种救命药物短缺的问题,呼吸道疾病患者需要了解以下信息。
吸入器并未出现供应短缺
出现短缺的只是在雾化器中使用的溶液。目前,沙丁胺醇吸入器供应充足,并且可能永远不会出现供应短缺问题。
这对于仅使用吸入器的轻症成年患者来说是好消息。但对于需要使用雾化器的患者而言,这却是坏消息。这类患者的病情通常更加严重。Oak Street Health的执行医疗总监约翰·舒曼博士表示,对于这类患者来说,雾化器通常是更好的选择,因为雾化器能够将药物送入肺部更深处。Oak Street Health是一家服务老年人的连锁初级护理诊所。他在俄克拉荷马州塔尔萨接诊患者。
专家们告诉《财富》杂志,雾化器通常还被用于儿童,无论病情严重程度,因为儿童很难根据医嘱恰当使用吸入器。雾化器还常被用于医院等医疗设施,因为重症病例通常会前往医院就诊。
医生可以开具一种类似的药物处方
舒曼称,好在对于沙丁胺醇,“有一种很好的替代选择”,它就是左旋沙丁胺醇。2008年在期刊《美国家庭医生》(American Family Physician)上发表的一篇论文显示,左旋沙丁胺醇用于治疗中度哮喘具有同样的效果,并且在副作用方面没有差异。目前这种药物未出现短缺。但随着需求增长,短缺可能会发生。
目前,沙丁胺醇短缺并未影响所有地区或所有患者
到目前为止,舒曼尚未发现任何受影响的患者。与欣克森的组织有合作的医院也未受到影响。但据他所知,一些儿科医院已经开始为使用雾化器的儿童开具左旋沙丁胺醇。如果使用沙丁胺醇的患者试图大量囤积,供应短缺的情况就会持续恶化。
现在更重要的是要注意肺部健康
欣克森指出,患者应该始终尽量避免哮喘的诱发因素,但现在这一点更加重要。每个人哮喘病发作的诱发因素不同,可能是疾病、感冒和吸烟。为了维持肺部的整体健康,美国肺脏协会(American Lung Association)建议烟民戒烟;采取措施改善室内空气质量;避免户外空气污染;定期就医接受检查等。
如果担心会因为沙丁胺醇供应短缺而受到影响,请联系医疗团队
欣克森表示,例如下一次开药时告诉你的药剂师,或者联系医生开具不同的药物处方。你还能够联系为你开处方的医生。(财富中文网)
译者:刘进龙
审校:汪皓
一种被用于治疗哮喘病发作的常见药物沙丁胺醇供应短缺,加剧了患者以及提供药物的药店和医疗设施的焦虑。
据美国食品与药品管理局(U.S. Food and Drug Administration)表示,硫酸沙丁胺醇吸入溶液自2022年秋天以来面临供应短缺。跟踪药物短缺情况的美国卫生系统药师协会(American Society of Health-System Pharmacists)称,该药物的主要生产商Akorn在今年2月关闭,严重影响了供应链。
沙丁胺醇是一种支气管扩张剂,可以通过放松气道的平滑肌来缓解哮喘病发作。美国呼吸治疗学会(American Association for Respiratory Care)的主席卡尔·欣克森对《财富》杂志表示,该药物还被用于治疗呼吸道合胞病毒(RSV)等呼吸道疾病,以及慢性阻塞性肺病(简称COPD,又被称为肺气肿)等慢性呼吸道疾病。
哪些人会受到影响?如果医生曾经为你开具沙丁胺醇处方,并且你尚未受到影响,未来你是否会受影响?关于这种救命药物短缺的问题,呼吸道疾病患者需要了解以下信息。
吸入器并未出现供应短缺
出现短缺的只是在雾化器中使用的溶液。目前,沙丁胺醇吸入器供应充足,并且可能永远不会出现供应短缺问题。
这对于仅使用吸入器的轻症成年患者来说是好消息。但对于需要使用雾化器的患者而言,这却是坏消息。这类患者的病情通常更加严重。Oak Street Health的执行医疗总监约翰·舒曼博士表示,对于这类患者来说,雾化器通常是更好的选择,因为雾化器能够将药物送入肺部更深处。Oak Street Health是一家服务老年人的连锁初级护理诊所。他在俄克拉荷马州塔尔萨接诊患者。
专家们告诉《财富》杂志,雾化器通常还被用于儿童,无论病情严重程度,因为儿童很难根据医嘱恰当使用吸入器。雾化器还常被用于医院等医疗设施,因为重症病例通常会前往医院就诊。
医生可以开具一种类似的药物处方
舒曼称,好在对于沙丁胺醇,“有一种很好的替代选择”,它就是左旋沙丁胺醇。2008年在期刊《美国家庭医生》(American Family Physician)上发表的一篇论文显示,左旋沙丁胺醇用于治疗中度哮喘具有同样的效果,并且在副作用方面没有差异。目前这种药物未出现短缺。但随着需求增长,短缺可能会发生。
目前,沙丁胺醇短缺并未影响所有地区或所有患者
到目前为止,舒曼尚未发现任何受影响的患者。与欣克森的组织有合作的医院也未受到影响。但据他所知,一些儿科医院已经开始为使用雾化器的儿童开具左旋沙丁胺醇。如果使用沙丁胺醇的患者试图大量囤积,供应短缺的情况就会持续恶化。
现在更重要的是要注意肺部健康
欣克森指出,患者应该始终尽量避免哮喘的诱发因素,但现在这一点更加重要。每个人哮喘病发作的诱发因素不同,可能是疾病、感冒和吸烟。为了维持肺部的整体健康,美国肺脏协会(American Lung Association)建议烟民戒烟;采取措施改善室内空气质量;避免户外空气污染;定期就医接受检查等。
如果担心会因为沙丁胺醇供应短缺而受到影响,请联系医疗团队
欣克森表示,例如下一次开药时告诉你的药剂师,或者联系医生开具不同的药物处方。你还能够联系为你开处方的医生。(财富中文网)
译者:刘进龙
审校:汪皓
A drug commonly used to treat asthma attacks is in short supply, increasing anxiety for patients who use it—and for pharmacies and health care facilities that provide it.
Albuterol sulfate inhalation solution has been in short supply since last fall, according to the U.S. Food and Drug Administration. A major manufacturer, Akorn, shut down in February, throwing a major wrench in the supply chain, according to the American Society of Health-System Pharmacists, which tracks drug shortages.
Albuterol is a bronchodilator that provides relief from asthma attacks by relaxing smooth muscles in the airways. But it’s also used to treat patients with respiratory illnesses like RSV, and chronic respiratory conditions like chronic obstructive pulmonary disease or COPD sometimes referred to as emphysema, Carl Hinkson, president of the American Association for Respiratory Care, tells Fortune.
Just who is affected? If you’ve been prescribed albuterol and haven’t been impacted yet, will you be in the future? Here’s what patients with respiratory disease need to know about the shortage of the life-saving drug.
Inhalers aren’t in short supply
The shortage is only of the liquid form, used in nebulizers. At the moment, albuterol inhalers aren’t in short supply and may never be.
It’s good news for adults with more mild disease who only use an inhaler. It’s not so good news for patients on nebulizers, who tend to have more severe disease. Nebulizers are often a better choice for such people because they seem to deliver medication more deeply into the lungs, Dr. John Schumann, executive medical director of Oak Street Health, a chain of primary care clinics that serve older adults. He sees patients in Tulsa, Okla.
Regardless of disease severity, nebulizers are also often prescribed for children, who have a hard time following directions to properly use an inhaler, experts tell Fortune. They’re also frequently used in health care facilities like hospitals due to the severity of cases seen there.
A similar drug can be prescribed
Thankfully, when it comes to albuterol, “there’s a good alternative available,” Schumann says: levalbuterol. It’s just as effective in treating moderate asthma, with no difference in side effects, according to a 2008 article in American Family Physician. And there’s currently no shortage of it. A shortage could occur, however, if demand increases.
Not all areas, or patients, are affected by the current shortage
So far, Schumann hasn’t seen any patients affected. And none of the hospitals Hinkson’s organization works with have been impacted yet. He does know, however, of some pediatric hospitals that have shifted to using levalbuterol for kids on nebulizers. The shortage could worsen, however, if those who use the drug attempt to sock up en masse.
It’s even more important now to be vigilant about your lung health
Patients should always seek to avoid triggers, but it’s even more crucial right now, Hinkson says. Triggers vary by person but can include illness, cold, and smoke. To maintain general lung health, the American Lung Association recommends quitting smoking, if you’re a smoker; taking steps to improve your indoor air quality; avoiding outdoor air pollution; and visiting your doctor for regular check-ups.
If you’re concerned you might be impacted by the albuterol shortage, contact someone on your health care team
This could be your pharmacist, who can see if you might be affected the next time you fill your prescription and contact your doctor for a different prescription, if so, Hinkson says. You could also contact your prescribing doctor.